1021 - The Surprising Gut + Energy Benefits of NAC (N-Acetylcysteine)

In this episode, Dr. Ruscio breaks down the surprising gut and systemic benefits of NAC (N-acetylcysteine), including how it may help break down biofilms, support SIBO and H. pylori treatment, improve gut lining repair, boost nutrient absorption, and support glutathione, mitochondria, and brain health. You'll also learn when sustained-release NAC may be useful, how to dose NAC properly, and what side effects or cautions to keep in mind.
✅ Start healing with us! Learn more about our virtual clinic: https://drruscio.com/virtual-clinic/
💊 Featured Products:
Biota Dissolve: https://store.drruscio.com/products/biota-dissolve
Jarrow Formulas N-A-C Sustain 600 mg: https://www.amazon.com/Jarrow-Formulas-Sustain-Supports-Function/dp/B0013OVVK0/
👇 Watch more videos like this 👇
➡️ Cure SIBO FASTER (New Research):
https://www.youtube.com/watch?v=u8MsOY5rgAU
➡️ 5 Reasons You Need Glutathione & How To Boost It:
https://www.youtube.com/watch?v=7k7YT70MnA4
➡️ 8 Ways to Beat Brain Fog & Boost Your Cognition:
https://www.youtube.com/watch?v=Tk_ICGk0RwQ
➡️ Butyrate – The SIBO Treatment Nobody Talks About:
https://www.youtube.com/watch?v=5B4l1yOn9UA
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And if you have any questions or topics you would like covered in the future, let me know in the comments!
👇 Read these next 👇
➡️ SIBO Biofilm Explained: Symptoms, Causes, and a Treatment Protocol:
https://drruscio.com/sibo-biofilm/
➡️ What are Biofilms?: https://drruscio.com/biofilms/
➡️ The Best Glutathione Foods (and When to Supplement):
https://drruscio.com/glutathione-foods/
➡️ 8 Best Microbiome Supplements for a Happier, Healthier Gut:
https://drruscio.com/best-microbiome-supplements/
📌 Timestamps
00:00 What is NAC?
01:47 H. pylori
04:50 SIBO & biofilms
11:00 Gut lining & nutrient absorption
15:22 IBD
18:18 Systemic benefits
24:16 Gut health protocol
26:14 Systemic protocol
27:29 Side effects
Supplementary endoscopy video reproduced from: Baumgartner M, Lang M, Holley H, et al. Mucosal Biofilms Are an Endoscopic Feature of Irritable Bowel Syndrome and Ulcerative Colitis. Gastroenterology (2021). Available on PubMed Central. Licensed under CC BY 4.0.
Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC8527885/
License: https://creativecommons.org/licenses/by/4.0/
Changes: trimmed
🎧 Audio Episode & Featured Studies
📉 N-acetylcysteine and intestinal health: https://pubmed.ncbi.nlm.nih.gov/25553484/
📉 Biofilm demolition and antibiotic treatment to eradicate resistant Helicobacter pylori:
https://pubmed.ncbi.nlm.nih.gov/20478402/
📉 N-acetylcysteine as an adjuvant therapy for Helicobacter pylori eradication: https://pubmed.ncbi.nlm.nih.gov/30746681/
📉 N-acetylcysteine as powerful molecule to destroy bacterial biofilms:
https://pubmed.ncbi.nlm.nih.gov/25339490/
📉 Mucosal Biofilms Are an Endoscopic Feature of Irritable Bowel Syndrome and Ulcerative Colitis:
https://pubmed.ncbi.nlm.nih.gov/34146566/
📉 Low dose rifaximin combined with N-acetylcysteine is superior to rifaximin alone in a rat model of IBS-D:
https://pubmed.ncbi.nlm.nih.gov/39103611/
📉 Biofilm Disruption Enhances Antimicrobial Therapy for Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth: https://pubmed.ncbi.nlm.nih.gov/41394228/
📉 Effect of N-acetylcysteine on remission maintenance in patients with ulcerative colitis: https://pubmed.ncbi.nlm.nih.gov/33067169/
📉 Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: https://pubmed.ncbi.nlm.nih.gov/33783984/
📉 N-Acetylcysteine Supplementation Elevates Human Brain Glutathione In Vivo: https://cds.ismrm.org/protected/17MProceedings/PDFfiles/4553.html?utm_
📉 Treatment effects of N-acetyl cysteine on resting-state functional MRI and cognitive performance in patients with chronic mild traumatic brain injury: https...