BONUS: Cholesterol, ApoB, and Lp(a) with Crystal Gossard, DCN, MS, CNS, LN

This episode is sponsored by Life Extension.
I am delighted to have Dr. Crystal Gossard, the Manager of Education at Life Extension, joining me today. Dr. Gossard is a Doctor of Clinical Nutrition with over 15 years of experience in nutrition, fitness, dietary supplements, and integrative functional medicine.
In our conversation today, Dr. Gossard and I discuss uncommon heart health testing, including gaps in care for women in perimenopause and menopause, and clarify the critical importance of a bioindividual personalized approach. We dive into specifics on labs, including ApoB as a direct measurement, the influence of glycation, insulin resistance and insulin sensitivity, LP(a), and high-sensitivity CRP as both a marker of systemic inflammation and a targeted inflammatory profile marker. We also cover oxidized LDL, inflammation and oxidative stress, the importance of CoQ10, and screening modalities like coronary artery calcium scoring, CCTA, CT angio, and Cleerly, and minerals, including magnesium and its role in over 600 enzymatic reactions in the body.
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IN THIS EPISODE, YOU WILL LEARN:
The importance of advanced lab testing for cardiovascular and metabolic health in women, particularly during perimenopause and menopause
What ApoB reveals about cardiovascular risk
Why Dr. Gossard considers LP(a) a one-and-done test
How elevated high-sensitivity CRP can indicate inflammation “simmering” in the background
How to manage inflammation through nutrition
How Dr. Gossard explains oxidized LDL
The value of CoQ10 for oxidized LDL
When should someone move beyond lab work to cardiovascular screening?
What magnesium testing can reveal
How magnesium supports the body
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