The Doctor Everyone Mocked — Until His 'Crazy' Theory Wiped Out a Killer Disease. Matt Kaplan - #547

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Matt Kaplan is a science journalist at The Economist and a trained paleontologist. His new book I Told You So!: Scientists Who Were Ridiculed, Exiled, and Imprisoned for Being Right is a candid investigation into how science actually works — and why the engine of discovery is badly in need of a tuneup.
In this conversation, we discuss why the pandemic exposed science's dirty secrets to the public, how Ignaz Semmelweis discovered handwashing saved lives and was thrown in an asylum for it, why Katalin Karikó survived where others didn't, the replication crisis and how funding models are making it worse, whether older scientists should control research dollars, why Galileo was never actually tortured, and what journalists and scientists must do differently before public trust collapses entirely.
Matt Kaplan also recently discussed science communication and dysfunction on other outlets — in this conversation, we go deeper on the replication crisis, the Semmelweis story, and why the funding model is quietly corrupting the scientific process.
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Key Takeaways
00:00 Why the pandemic was science's most damaging moment of exposure
03:30 The scientific-industrial press complex — and who's really to blame
06:50 How science journalism fails the public 85% of the time
10:00 Ignaz Semmelweis: the man who proved handwashing saves lives and was destroyed for it
20:10 Why infection rates dropped from 21% to zero — and nobody listened
24:30 What Katalin Karikó had that Semmelweis didn't: shelter
28:00 The replication crisis — why nobody is funding the most important work in science
33:00 How funding models force scientists to run experiments they've already won
40:30 Should older scientists control research dollars? A Nobel laureate weighs in
43:45 Why Galileo was never tortured — and why the myth won't die
47:00 The rhinoceros tooth: a paleontologist's lesson in confirmation bias
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