Feb 27 2026 This Week in Cardiology

A superb note on CPR and DNR orders, patients' vs doctors' preferences for statins, more on GLP-1s, another LAAC story, and some closing cautionary notes on PFA are the topics John Mandrola, MD, discusses in this week's podcast.
This podcast is intended for healthcare professionals only.
To read a partial transcript or to comment, visit:
https://www.medscape.com/twic
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Addressing Inadequate Documentation of Unilateral DNR https://jamanetwork.com/journals/jama/fullarticle/2829203
Video: Can We Talk About CPR? https://www.youtube.com/watch?v=yTCRfY3ETvI
Personal Reminiscences of CPR's Origin https://www.ajconline.org/article/S0002-9149(03)00977-9/pdf
II Public Preferences for Statin Therapy
Measuring Public Preferences for Statin Therapy https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2844660
III GLP-1 RA News
ACHIEVE Trial https://doi.org/10.1016/S0140-6736(26)00202-3
IV New Trial in GLP-1 for Patients with AF
Seminal-AF Trial https://clinicaltrials.gov/study/NCT06499857
V Relationship between Spontaneous Echo Contrast and LAAC Outcomes
OCEAN-LAAC Trial https://doi.org/10.1016/j.jacep.2025.09.028
News Release on Upcoming LAAOS-4 trial https://www.phri.ca/watchman/
Reading the "Smoke" -- Editorial on OCEAN-LAAC https://www.jacc.org/doi/10.1016/j.jacep.2025.10.029
VI Concluding Remarks on My Talk at Western AF
Delayed Myocardial Ischemia and Malignant Arrhythmias After PFA https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.125.077983
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