Jun 05 2026 This Week in Cardiology

Chemical cardioversion in the ED, HF monitoring, weight loss in AF, and surgical LAA excision are the topics John Mandrola, MD, discusses in this week's podcast.
This podcast is intended for healthcare professionals only.
To read a partial transcript or to comment, visit:
https://www.medscape.com/twic
I Chemical Cardioversion of AF in the ED: The FLECA-ED Trial
FLECA-ED Rationale paper https://pmc.ncbi.nlm.nih.gov/articles/PMC10299428/
FLECA-ED ESC Slides https://esc365.escardio.org/presentation/321209
Review on Flecainide Use Despite CAST https://doi.org/10.1016/j.hrthm.2025.08.034
RACE 7 ACWAS Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1900353
II Heart Failure Monitoring – The ALLEVIATE-HF Trial
ALLEVIATE-HF Trial https://doi.org/10.1016/j.jacc.2026.03.075
CHAMPION Trial https://doi.org/10.1016/S0140-6736(11)60101-3
GUIDE HF Trial https://doi.org/10.1016/S0140-6736(21)01754-2
ALLEVIATE-HF Editorial: Alerts Are Not Treatment https://doi.org/10.1016/j.jacc.2026.04.014
Steve Stiles Medscape report on CHAMPION https://www.medscape.com/viewarticle/755189
III A Negative Weight Loss Study in AF
LOSE-AF Trial https://jamanetwork.com/journals/jama/fullarticle/2849335
IV Surgical LAA Excision
OPINION Trial https://doi.org/10.1093/eurheartj/ehaf674
LAAOS 3 trial https://www.nejm.org/doi/full/10.1056/NEJMoa2101897
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