Jun 26 2026 This Week in Cardiology

Listener feedback on valvular heart disease, statins and frailty, left atrial posterior wall ablation fails again, interpreting medical tests and AI ECG reading are the topics John Mandrola, MD, discusses in this week's podcast.
This podcast is intended for healthcare professionals only.
To read a partial transcript or to comment, visit:
https://www.medscape.com/twic
I Listener Feedback
PREVUE-VALVE Study https://www.jacc.org/doi/10.1016/j.jacc.2026.02.5137
II Statins and Frailty
Statin Initiation Tied to Lower Frailty Risk in Older Adults https://www.medscape.com/viewarticle/statin-initiation-tied-lower-frailty-risk-older-adults-2026a1000lec
Statins and Survival Free of Incident Frailty https://doi.org/10.1093/eurheartj/ehag451
III LA Posterior Wall Isolation Fails Again
CORNERSTONE Trial https://doi.org/10.1093/eurheartj/ehag486
CAPLA Trial https://jamanetwork.com/journals/jama/fullarticle/2800186
IV Does the Display of Test Results Improve Clinical Decisions?
Interval Likelihood Ratios for Clinical Decsion-Making https://evidence.nejm.org/doi/full/10.1056/EVIDoa2500249
Making Sense of Health Statistics https://journals.sagepub.com/doi/full/10.1111/j.1539-6053.2008.00033.x
V AI and the ECG and Saving Doctors
Case Report — AI-Enhanced Diagnostics https://www.nature.com/articles/s41591-026-04454-y
The New York Times article https://www.nytimes.com/2026/06/22/health/artificial-intelligence-heart-damage.html
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The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington
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