Oct 31 2025 This Week in Cardiology

Four pillars of cardiology today, stable coronary artery disease, severe aortic stenosis, the evaluation of chest pain, and best therapies for atrial fibrillation are the topics John Mandrola, MD, discusses in this week's podcast.
This podcast is intended for healthcare professionals only.
To read a partial transcript or to comment, visit:
https://www.medscape.com/twic
I Stable CAD Complete vs culprit-only revascularization at time of STEMI
iMODERN Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2512918
PRAMI Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1305520
COMPLETE Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1907775
FULL REVASC Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2314149
PCI Revascularization Strategies After MI https://www.jacc.org/doi/10.1016/j.jacc.2024.04.051
CULPRIT SHOCK Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1710261
How a Meta-Analysis Can Mislead https://www.sensible-med.com/p/how-a-meta-analysis-can-misleadthe
II SEVERE Aortic Senosis
7-Year PARTNER 3 Results – TAVI vs SAVR
7-year results PARTNER 3 https://www.nejm.org/doi/full/10.1056/NEJMoa2509766
PARTNER 3 at 1 year https://www.nejm.org/doi/10.1056/NEJMoa1814052
PARTNER 3 at 5 years https://www.nejm.org/doi/10.1056/NEJMoa2307447
III Functional vs Anatomic Assessment in Suspected CAD
10-year follow-up of PROMISE trial https://jamanetwork.com/journals/jamacardiology/fullarticle/2838118
PROMISE Trial https://www.nejm.org/doi/10.1056/NEJMoa1415516
CCTA vs Functional Stress Test – Meta-Analysis https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2655243
IV ARREST AF
ARREST AF trial https://jamanetwork.com/journals/jamacardiology/fullarticle/2840225
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